Buprenorphine plus naloxone, a new substitution treatment

Suboxone, a combination of buprenorphine and the opiate antagonist naloxone, is a substitution treatment for opioid drug dependence intended to reduce potential abuse by intravenous injection. In our New products review Steve Chaplin presents the clinical data relating to its efficacy and adverse effects, and Dr Alan Fraser comments on its place in therapy. Copyright © 2007 Wiley Interface Ltd