Rituximab: first monoclonal antibody for severe, active RA

Rituximab (MabThera) is a monoclonal antibody that exerts a novel anti‐inflammatory action in rheumatoid arthritis via B‐cell depletion. In our New products review Michael Guida presents the clinical data relating to its efficacy and adverse effects, and Dr Michael Plant comments on its place in therapy. Copyright © 2007 Wiley Interface Ltd