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Angiotensin-II receptor blockers (ARBs) are associated with a reduced risk of developing dementia and the benefit is doubled in combination with ACE inhibitors, a US cohort study suggests (BMJ 2010;340:b5465).

The US regulatory authority has concluded that tiotropium (Spiriva) is not associated with an increased risk of stroke, MI or cardiovascular death.

The Department of Health has chosen Wyeth’s Prevenar 13 as the pneumococcal vaccine for the national immunisation programme.

he Government has expressed ‘sincere regret and deep sympathy for the injury and suffering endured by all those affected when expectant mothers took the drug thalidomide between 1958 and 1961’.

Phenytoin should be avoided if alternative treatment is possible in patients of Han Chinese and Thai origin, warns the MHRA in its latest Drug Safety Update (2010;3: Issue 6) (www. mhra.gov.uk).

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