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Combinations of disease-modifying agents (DMARDs) are as effective as a biological agent plus methotrexate in slowing radiographic progression in patients with rheumatoid arthritis, according to US analysts (Arthr Rheum 2010; published online. doi: 10.1002/art. 27592).

The 2008/09 National Diabetes Audit for England and Wales shows that treatment targets are not being met for many people with diabetes despite annual contact with 90 per cent of patients (www.ic.nhs.uk).

ARBs may be associated with a slight increase in the risk of cancer, a meta-analysis suggests (Lancet Oncology 2010; doi:10.1016/S1470-2045(10) 70106-6).

The ban on smoking in public places in England was followed by a small but statistically significant reduction in emergency admissions for MI, say researchers from Bath University (BMJ 2010;340:c2161).

The National Patient Safety Agency (www.nrls. npsa.nhs.uk) has issued an alert on the safe administration of insulin.

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