Articles: 25.01-2 January 2014

Constella: new treatment for constipation-predominant IBS

Linaclotide (Constella) is guanylate cyclase-C receptor agonist for the treatment of constipation-predominant IBS. In our New products review, Steve Chaplin presents the clinical data relating to its efficacy and adverse effects and Dr Nigel Trudgill discusses its place in therapy.
Constella new treatment for constipation predominant …

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No association seen between standard-dose NSAIDs and progression of moderate CKD

Low or moderate doses of NSAIDs appear to be safe for patients with moderate chronic kidney disease (CKD): estimated glomerular filtration rate (eGFR) = 30–90ml per minute. High-dose NSAIDs should be avoided.
No association seen between standard dose NSAIDs and progression of moderate CKD

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OptimiseRx: patient-specific guidance for GP prescribing

OptimiseRx is a new decision support system produced by First Databank. Here, the author explains what it does and how it can aid GP prescribing decisions.
OptimiseRx patient specific guidance for GP prescribing

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Pharmacists as dispensers and formation of the PPA

In our series on the history of prescribing policy, Dr Darrin Baines traces how successive governments have attempted to curb drug costs. Here, he explains how pharmacists became dispensers and how the Joint Pricing Committee was replaced by the PPA.
Pharmacists as dispensers and formation of …

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Latest reviews from Cochrane

In this section we present an abstract of a review relevant to prescribing in general practice from the latest issue of The Cochrane Database of Systematic Reviews. To view the article in full or for further information, visit www.thecochranelibrary.com
Phosphodiesterase type4 inhibitors for COPD

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Recommended diagnosis and management of insomnia

Insomnia can cause impaired daytime functioning and reduced quality of life. In our Drug review the authors discuss its diagnosis and the available treatment options, followed by an analysis of the prescription data and sources of further information.
Recommended diagnosis and management of insomnia

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Ten things GPs need to know about pharmacists

Steve Chaplin describes a new guide for GPs that aims to foster a better understanding of the role of community pharmacists.
Ten things GPs need to know about pharmacists

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Updated NICE guidance on secondary prevention post-MI

The new NICE guideline on secondary prevention following an MI offers a comprehensive update on standards of care. This is a substantial document covering drug therapy, lifestyle advice and cardiac rehabilitation and is cross-referenced to multiple other NICE guidelines.
Updated NICE guidance on secondary prevention post-MI

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