Articles: 24.13-16 July-August 2013

A worsening rash with steroids

This 70-year-old man developed an erythematous scaly plaque on his left knee. Having previously had ‘a bit of trouble’ with eczema, he assumed it to be the same problem and applied some betamethasone cream he still had in the cupboard.
A worsening rash with steroids

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Big Data: not just a lot more data

For over two decades, the NHS has had easy access to accurate and plentiful prescribing data. Since the introduction of the Prescribing Analysis and CosT (PACT) database in the late-1980s, millions of pieces of information have been routinely produced and analysed on doctor drug choice.
Big …

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Current choice of treatment for hypo- and hyperthyroidism

Thyroid dysfunction is a common disorder and most cases of hypothyroidism are managed in general practice. Our Drug review discusses the currently available drug treatments for hypo- and hyperthyroidism, followed by sources of further information in Resources.
Current choice of treatment for hypo and hyperthyroidism

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Illustrating risk vs benefit with the tiotropium Respimat inhaler

Patient decision aids present evidence-based estimates of the risks and benefits of a particular treatment. Here, Dr Chris Cates illustrates the benefit of tiotropium in reducing exacerbations in COPD and the increased risk of mortality associated with administration via the Respimat inhaler.
Illustrating risk vs benefit …

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Mirabegron: new treatment for OAB with fewer side-effects

Mirabegron (Betmiga) is a new class of drug for the treatment of overactive bladder. In our New products review, Steve Chaplin presents the clinical data relating to its efficacy and adverse events, and Professor Chapple discusses its place in treatment compared with anticholinergics.
Mirabegron new treatment …

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New from NICE

Clinical guideline. Familial breast cancer: classification and care of people at risk of familial breast cancer and management of breast cancer and related risks in people with a family history of breast cancer.
New from NICE

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Latest reviews from Cochrane

In this section we present an abstract of a review relevant to prescribing in general practice from the latest issue of The Cochrane Database of Systematic Reviews. To view the article in full or for further information, visit www.thecochranelibrary.com
Pharmacological interventions for smoking cessation an overview …

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Ramipril increases pain-free walking time in patients with intermittent claudication

Ramipril significantly increased both the pain-free walking time and maximum walking time in patients with peripheralartery disease (PAD) and intermittent claudication. It is uncertain whether other ACE inhibitors are similarly effective.
Ramipril increases pain free walking time in patients with intermittent claudication

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Withdrawing life-extending drugs at the end of life

Our series on stopping drugs provides practical advice on why, when and how to withdraw drug therapy. Here the author discusses the reasons for discontinuing life-extending medications during end-of-life care.
Withdrawing life extending drugs at the end of life

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