Articles: 28.03 March 2017

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Next generation immunology: the quest for a universal vaccine

Until recently, vaccine development involved isolating, inactivating and injecting the pathogen or part of the micro-organism. However, newer approaches such as reverse vaccinology are facilitating the synthesis of novel vaccine antigens, and may offer hope for a ‘universal vaccine’ in the future.
Despite the controversies that …

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The treatment of URTIs and otitis media in children

Despite the majority of infections being viral and self-limiting, children are still frequently prescribed antibiotics for upper respiratory tract infections (URTIs) and acute otitis media. This article discusses how to assess whether an antibiotic is appropriate and when referral to secondary care may be necessary.
The …

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Legal implications of deprescribing: a case scenario

Prescribers are increasingly being encouraged to deprescribe unnecessary medication, but a potential barrier is the worry of litigation. This article presents an illustrative case scenario that examines the legal implications of deprescribing.
The practice of deprescribing medication is being encouraged to support reducing inappropriate polypharmacy.1-3 However, …

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