Full content PDFs

Antimicrobial resistance – time to start spending
The failure of antibiotics to treat common infections is a growing and alarming threat. The possibility that prescribers may soon be turning away patients with, for example, gonorrhoea, may only be a few short years away. While researchers are finding novel uses for existing medicines and developing innovative techniques such as nano-engineering to address the problem, a co-ordinated global response from governments, health agencies and the pharmaceutical industry is clearly needed.
Rob Munro

Antimicrobial resistance and the race to find new antibiotics
The race is on for researchers to develop new classes of antibiotic to tackle the global crisis of increasing antimicrobial resistance (AMR). But with few new antibiotics against Gram-positive bacteria becoming available in recent years, and no new class of antibiotic for Gram-negative infections for more than 40 years, what hope is there on the horizon?
Danny Buckland

British Pharmacological Society: supporting safer prescribing
Professor David Webb is president of the British Pharmacological Society (BPS) and Christison professor of therapeutics and clinical pharmacology at the University of Edinburgh. He is also a nonexecutive director of the Medicines and Healthcare products Regulatory Agency (MHRA), and lead clinician at the Edinburgh Hypertension Excellence Centre. He talks to Angela Dowden about his passion for pharmacology and his work guiding the BPS into the future.
Angela Dowden

Management of panic disorder in primary care
(click here for full web article) 
Panic disorder is a common presentation in primary care and in recent years, evidence supporting the use of many drug treatments and psychotherapies has emerged. This article discusses the diagnosis and clinical assessment of panic disorder and examines the efficacy of the pharmacological and psychological treatment options available.
Simon Davies, Jon Nash and David Nutt

Adverse drug reactions: prescribing’s twilight zone
Published studies cannot be fully relied upon to provide all the information needed about adverse drug reactions (ADRs), so there is a pressing need to improve ADR reporting by healthcare professionals and patients. For many years, the Yellow Card Scheme has offered an early warning signal for ADRs, but the scheme still needs be more widely used, and to be fully integrated into clinical systems.
Mark Greener

Detection and recommended treatment of head lice
(click here for full web article)
Head lice infestations are very common in school-age children and can be difficult to eradicate. This article discusses how to detect head lice, and considers the treatments options available and their efficacy, including physical removal of lice (wet combing), physical insecticides and chemical insecticides.
Chin Whybrew

Prevention and treatment of age-related macular degeneration
(click here for full web article)
Age-related macular degeneration (AMD) is a common cause of visual loss in older people and GPs play a critical role in identification and timely referral. This article discusses the features of AMD, preventing progression, treatment options, and the GP’s role in management.
Sarah Horton and Catherine Guly

Frailty and treatments for benign prostatic hyperplasia
Many older men are likely to have lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). Having LUTS can increase the risk of frailty, and the drugs used to treat the symptoms can exacerbate the problem. This article examines these risks and how they can be reduced.
Steve Chaplin

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